This business guide provides a framework for understanding the Intrapreneurship Ecosystem – the complex set of processes, practices, resources and relationships which collectively serve to facilitate or inhibit intrapreneurship and social innovation.  It is a key output of the Intrapreneur Systems Challenge which was jointly hosted by Business Fights Poverty and The League of Intrapreneurs with support from DFID, CEMEX and The BMW Foundation. The guide identifies key components of the intrapreneurship ecosystem and suggests practical steps that companies can take to strengthen the supporting environment for social innovation inside their organisations.